2024 -- S 2820

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LC004443

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     STATE OF RHODE ISLAND

IN GENERAL ASSEMBLY

JANUARY SESSION, A.D. 2024

____________

A N   A C T

RELATING TO FOOD AND DRUGS -- UNIFORM CONTROLLED SUBSTANCES ACT

     

     Introduced By: Senators Valverde, Euer, DiMario, and Miller

     Date Introduced: March 22, 2024

     Referred To: Senate Health & Human Services

     (Dept of Health)

It is enacted by the General Assembly as follows:

1

     SECTION 1. Section 21-28-2.1 of the General Laws in Chapter 21-28 entitled "Uniform

2

Controlled Substances Act" is hereby amended to read as follows:

3

     21-28-2.01. Authority to control — Registration requirements and procedures.

4

     (a)(1) The director of the department of health shall control all substances enumerated in § 

5

21-28-2.08 or the most current version of Title 21 of the Code of Federal Regulations (CFR) and

6

may by motion or on the petition of any interested party pursuant to the procedures of chapter 35

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of title 42, the Administrative Procedures Act, add, reschedule, or delete a substance as a controlled

8

substance. In making this determination, the director of health shall consider, but not be limited to

9

the following:

10

     (i) ( Its actual or relative potential for abuse;

11

     (ii) Scientific evidence of its pharmacological effect if known;

12

     (iii) State of current scientific knowledge regarding the substance;

13

     (iv) Its history and current pattern of abuse;

14

     (v) The scope, duration, and significance of abuse;

15

     (vi) What, if any, risk there is to the public health;

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     (vii) Its psychic or physiological dependence liability;

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     (viii) Whether the substance is an immediate precursor of a substance already controlled

18

under this chapter.

19

     (2) After considering the factors in subdivision (1) of this section the director of health

 

1

shall make findings with respect to these factors and shall issue an order controlling the substance

2

if it is found that the substance has potential for abuse.

3

     (b) If the director of health designates a substance as an immediate precursor, substances

4

which are precursors of the controlled precursor shall not be subject to control solely because they

5

are precursors of the controlled precursor.

6

     (c) If any substance is designated, rescheduled, or deleted as a controlled substance under

7

federal law and notice of that action is given to the director of health, he or she shall similarly

8

control the substance under this chapter after the expiration of sixty (60) days from publication in

9

the federal register of a final order designating a substance as a controlled substance or rescheduling

10

or deleting a substance, unless within that sixty (60) day period, the director of health objects to

11

inclusion, rescheduling, or deletion. In that case, the director of health shall publish the reasons for

12

objection and afford all interested parties an opportunity to be heard. At the conclusion of the

13

hearing, the director of health shall publish his or her decision, which shall be final unless altered

14

by statute. The director of health shall publish and file his or her decision with the secretary of state.

15

Upon publication of objection to inclusion, rescheduling, or deletion under this chapter by the

16

director of health, control under this chapter is stayed until the director of health publishes his or

17

her decision. The director of the department of health shall reference the current version of Title 21

18

of the CFR as the current list of substances designated, rescheduled, or deleted as a controlled

19

substance for the state. If the director objects to inclusion, rescheduling, or deletion of any substance

20

under the current federal law, the director shall file that decision with the secretary of state and post

21

exempted substances on the department of health website.

22

     (d) The following persons need not register and may lawfully possess controlled substances

23

under this chapter:

24

     (1) An agent or employee of any registered manufacturer, distributor, or dispenser of any

25

controlled substance if he or she is acting in the usual course of his or her business or employment;

26

     (2) A common or contract carrier or warehouse operator, or an employee of a carrier or

27

warehouse operator, whose possession of any controlled substance is in the usual course of business

28

or employment;

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     (3) An ultimate user or a person in possession of any controlled substance pursuant to a

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lawful order of a practitioner or in lawful possession of a schedule V substance.

31

     (e) The director of health may waive by rule the requirement for registration of certain

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manufacturers, distributors, or dispensers if he or she finds it consistent with the public health and

33

safety.

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     (f) A separate registration is required at each place of business where the applicant

 

LC004443 - Page 2 of 20

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manufactures, distributes, or dispenses controlled substances. A separate registration is required at

2

each place of professional practice at which a practitioner stores controlled substances. A

3

practitioner may prescribe and administer controlled substances, upon registering with the director

4

of health at the applicant’s principal place of professional practice.

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     (g) The director of health or his or her authorized agent may inspect the establishment of a

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registrant or applicant for registration in accordance with his or her regulations.

7

     SECTION 2. Sections 21-28-2.8, 21-28-2.9 and 21-28-2.10 of the General Laws in Chapter

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21-28 entitled "Uniform Controlled Substances Act" are hereby repealed.

9

     21-28-2.08. Contents of schedules.

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     Schedules I through V shall consist of the drugs and other substances, by whatever official

11

name, common or usual name, chemical name, or brand name designated, listed in the

12

corresponding section, or designated by the director of the department of health pursuant to § 21-

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28-2.01.

14

     Schedule I

15

     (a) Opiates. Unless specifically excepted or unless listed in another schedule, any of the

16

following opiates, including its isomers, esters, ethers, salts, and salts of isomers, esters, and ethers

17

whenever the existence of the isomers, esters, ethers, and salts is possible within the specific

18

chemical designation:

19

     (1) Acetylmethadol

20

     (2) Allylprodine

21

     (3) Alphacetylmethadol

22

     (4) Alphameprodine

23

     (5) Alphamethadol

24

     (6) Benzethidine

25

     (7) Betacetylmethadol

26

     (8) Betameprodine

27

     (9) Betamethadol

28

     (10) Betaprodine

29

     (11) Clonitazene

30

     (12) Dextromoramide

31

     (13) Difenoxin

32

     (14) Diampromide

33

     (15) Diethylthiambutene

34

     (16) Dimenoxadol

 

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     (17) Dimepheptanol

2

     (18) Dimethylthiambutene

3

     (19) Dioxaphetyl butyrate

4

     (20) Dipipanone

5

     (21) Ethylmethylthiambutene

6

     (22) Etonitazene

7

     (23) Extoxerdine

8

     (24) Furethidine

9

     (25) Hydroxypethidine

10

     (26) Ketobemidone

11

     (27) Levomoramide

12

     (28) Levophenacylmorphan

13

     (29) Morpheridine

14

     (30) Noracymethadol

15

     (31) Norlevorphanol

16

     (32) Normethadone

17

     (33) Norpipanone

18

     (34) Phenadoxone

19

     (35) Phenampromide

20

     (36) Phenomorphan

21

     (37) Phenoperidine

22

     (38) Piritramide

23

     (39) Proheptazine

24

     (40) Properidine

25

     (41) Propiram

26

     (42) Racemoramide

27

     (43) Trimeperidone

28

     (44) Tilidine

29

     (45) Alpha-methylfentanyl

30

     (46) Beta-hydroxy-3-methylfentanyl other names:

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     N-[1-(2hydroxy-2-phenethyl)-3-methyl-4piperidingyl]-Nphenylpropanamide

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     (47) Alpha-methylthiofentanyl (N-[1-methyl-2-(2-thienyl)ethyl-4-piperidinyl]-N-

33

phenylpropanamide)

34

     (48) N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide, its optical, positional, and

 

LC004443 - Page 4 of 20

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geometric isomers, salts and salts of isomers (Other names: acetyl fentanyl)

2

     (49) N-[1-[2-hydroxy-2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenyl propionamide

3

(Other names: beta-hydroxythiofentanyl)

4

     (50) N-(1-phenethylpiperidin-4-yl)-N-phenylbutyramide (Other names: Butyryl fentanyl)

5

     (51) N-(1-phenethylpiperidin-4-yl)-N-phenylfuran-2-carboxamide (Other names: Furanyl

6

fentanyl)

7

     (52) 3,4-dichloro-N-[(1-dimethylamino) cyclohexylmethyl]benzamide (Other names: AH-

8

7921)

9

     (53) 3,4-Dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (Other names:

10

U-47700)

11

     (54) 3-Methylbutyrfentanyl (Other names: 3-MBF)

12

     (55) 4-Fluorobutyrfentanyl (Other names: 4-FBF, p-FBF)

13

     (56) 4-Phenylfentanyl

14

     (57) 4-Methoxybutyrfentanyl (Other names: 4-MeO-BF)

15

     (58) Acrylfentanyl (Other names: acryloyfentanyl)

16

     (59) Lofentanyl

17

     (60) N-Methylcarfentanyl

18

     (61) Ocfentanyl (INN, A-3217)

19

     (63) 4-methoxymethylfentanyl (Other names: R-30490)

20

     (64) 1-cyclohexyl-4-(1,2 diphenylethyl)piperazine) (Other names: MT-45, IC-6)

21

     (b) Opium Derivatives. Unless specifically excepted or unless listed in another schedule,

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any of the following opium derivatives, its salts, isomers, and salts of isomers whenever the

23

existence of the salts, isomers, and salts of isomers is possible within the specific chemical

24

designation:

25

     (1) Acetorphine

26

     (2) Acetyldihydrocodeine

27

     (3) Benzylmorphine

28

     (4) Codeine methylbromide

29

     (5) Codeine-N-Oxide

30

     (6) Cyprenorphine

31

     (7) Desomorphine

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     (8) Dihydromorphine

33

     (9) Etorphine (Except hydrochloride salt)

34

     (10) Heroin

 

LC004443 - Page 5 of 20

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     (11) Hydromorphinol

2

     (12) Methyldesorphine

3

     (13) Methylihydromorphine

4

     (14) Morphine methylbromide

5

     (15) Morphine methylsulfonate

6

     (16) Morphine-N-Oxide

7

     (17) Myrophine

8

     (18) Nococodeine

9

     (19) Nicomorphine

10

     (20) Normorphine

11

     (21) Pholcodine

12

     (22) Thebacon

13

     (23) Drotebanol

14

     (c) Hallucinogenic Substances. Unless specifically excepted or unless listed in another

15

schedule, any material, compound, mixture, or preparation that contains any quantity of the

16

following hallucinogenic substances, or that contains any of its salts, isomers, and salts of isomers

17

whenever the existence of the salts, isomers, and salts of isomers is possible within the specific

18

chemical designation (for purposes of this subsection only, the term “isomer” includes the optical,

19

position, and geometric isomers):

20

     (1) 3, 4-methylenedioxy amphetamine

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     (2) 5-methoxy-3, 4-methylenedioxy amphetamine

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     (3) 3, 4, 5-trimethoxy amphetamine

23

     (4) Bufotenine

24

     (5) Diethyltryptamine

25

     (6) Dimethyltryptamine

26

     (7) 4-methyl 2, 5-dimethoxyamphetamine

27

     (8) Ibogaine

28

     (9) Lysergic acid diethylamide

29

     (10) Marihuana

30

     (11) Mescaline

31

     (12) Peyote. Meaning all parts of the plant presently classified botanically as Lophophora

32

Williamsii Lemair whether growing or not; the seeds of the plant; any extract from any part of the

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plant; and any compound, manufacture, salt, derivative, mixture, or preparation of the plant, its

34

seeds or extracts.

 

LC004443 - Page 6 of 20

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     (13) N-ethyl-3-piperidyl benzilate

2

     (14) N-methyl-3-piperidyl benzilate

3

     (15) Psilocybin

4

     (16) Psilocyn

5

     (17) Tetrahydrocannabinols. Synthetic equivalents of the substances contained in the plant,

6

or in the resinous extractives of Cannabis, sp. and/or synthetic substances, derivatives, and their

7

isomers with similar chemical structure and pharmacological activity such as the following: delta

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1 cis or trans tetrahydrocannabinol, and their optical isomers. Delta 6 cis or trans

9

tetrahydrocannabinol and their optical isomers. Delta 3, 4 cis or trans tetrahydrocannabinol and

10

their optical isomer. (Since nomenclature of these substances is not internationally standardized,

11

compounds of these structures, regardless of numerical designation of atomic positions covered).

12

     (18) Thiophene analog of phencyclidine. 1-(1-(2 thienyl) cyclo-hexyl) pipiridine: 2-

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Thienyl analog of phencyclidine: TPCP

14

     (19) 2,5 dimethoxyamphetamine

15

     (20) 4-bromo-2,5-dimethoxyamphetamine, 4-bromo-2,5-dimethoxy-alpha-

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methylphenethyamine: 4-bromo-2,5-DMA

17

     (21) 4-methoxyamphetamine-4-methoxy-alpha-methylphenethylaimine:

18

paramethoxyamphetamine: PMA

19

     (22) Ethylamine analog of phencyclidine. N-ethyl-1-phenylcyclohexylamine, (1-

20

phenylcyclohexyl) ethylamine, N-(1-phenylcyclophexyl) ethylamine, cyclohexamine, PCE

21

     (23) Pyrrolidine analog of phencyclidine. 1-(1-phencyclohexyl)-pyrrolidine PCPy, PHP

22

     (24) Parahexyl; some trade or other names: 3-Hexyl-1-hydroxy-7,8,9,10-tetrahydro-6,6,9-

23

trimethyl-6H-dibenz o (b,d) pyran: Synhexyl.

24

     (25) Salvia Divinorum (Salvinorin A or Divinorin A), meaning any extract from any part

25

of the plant, and any compound, salt derivative, or mixture of the plant or its extracts. This shall

26

not mean the unaltered plant.

27

     (26) Datura stamonium (jimsom weed or datura), meaning any extract from any part of the

28

plant, and any compound, salt derivative, or mixture of the plant or its extracts. This shall not mean

29

the unaltered plant.

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     (d) Depressants. Unless specifically excepted or unless listed in another schedule, any

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material, compound, mixture, or preparation that contains any quantity of the following substances

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having a depressant effect on the central nervous system, including its salts, isomers, and salts of

33

isomers whenever the existence of the salts, isomers, and salts of isomers is possible within the

34

specific chemical designation:

 

LC004443 - Page 7 of 20

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     (1) Mecloqualone.

2

     (2) Methaqualone.

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     (3) 3-methyl fentanyl (n-(3methyl-1(2-phenylethyl)-4-piperidyl)-N-phenylpropanamide.

4

     (4) 3,4-methyl-enedioxymethamphetamine (MDMA), its optical, positional, and geometric

5

isomers, salts, and salts of isomers.

6

     (5) 1-methyl-4-phenyl-4-propionoxypiperidine (MPPP), its optical isomers, salts, and salts

7

of isomers.

8

     (6) 1-(2-phenylethyl)-4-phenyl-4-acetyloxypiperidine (PEPAP), its optical isomers, salts,

9

and salts of isomers.

10

     (7) N-(1-(1-methyl-2-phenyl)ethyl-4-piperidyl)-N-phenyl-acetamide (acetyl-

11

alphamethylfentanyl), its optical isomers, salts, and salts of isomers.

12

     (8) N-(1-(1-methyl-2(2-thienyl)ethyl-4-piperidyl)-N-phenylpropanami de (alpha-

13

methylthiofentanyl), its optical isomers, salts, and salts of isomers.

14

     (9) N-(1-benzyl-piperidyl)-N-phenylpropanamide (benzyl-fentanyl), its optical isomers,

15

salts, and salts of isomers.

16

     (10) N-(1-(2-hydroxy-2-phenyl)ethyl-4-piperidyl)-N-phenyl-propanamid e (beta-

17

hydroxyfentanyl), its optical isomers, salts, and salts of isomers.

18

     (11) N-(3-methyl-1(2-hydroxy-2-phenyl)ethyl-4-piperidyl)-N-phenylpro panamide (beta-

19

hydroxy-3-methylfentanyl), its optical and geometric isomers, salts, and salts of isomers.

20

     (12) N-(3-methyl)-1-(2-(2-thienyl)ethyl-4-piperidyl)-N-phenylpro-panamide (3-

21

methylthiofentanyl), its optical and geometric isomers, salts, and salts of isomers.

22

     (13) N-(1-2-thienyl)methyl-4-piperidyl)-N-phenylpropanamide (thenylfentanyl), its

23

optical isomers, salts, and salts of isomers.

24

     (14) N-(1-(2(2-thienyl)ethyl-4-piperidyl-N-phenylpropanamide (thiofentanyl), its optical

25

isomers, salts, and salts of isomers.

26

     (15) N-[1-(2-phenylethyl)-4-piperidyl]-N-(4-fluorophenyl)-propanamid e (para-

27

fluorofentanyl), its optical isomers, salts, and salts of isomers.

28

     (16) Gamma hydroxybutyrate, HOOC-CH2-CH2-CH2OH, its optical, position, or

29

geometric isomers, salts, and salts of isomers.

30

     (17) Etizolam.

31

     (18) Flubromazolam.

32

     (e) Stimulants. Unless specifically excepted or unless listed in another schedule, any

33

material, compound, mixture, or preparation that contains any quantity of the following substances

34

having a stimulant effect on the central nervous system, including its salts, isomers, and salts of

 

LC004443 - Page 8 of 20

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isomers:

2

     (1) Fenethylline

3

     (2) N-ethylamphetamine

4

     (3) 4-methyl-N-methylcathinone (Other name: mephedrone)

5

     (4) 3,4-methylenedioxy-N-methlycathinone (Other name: methylone)

6

     (5) 3,4-methylenedioxypyrovalerone (Other name: MDPV)

7

     (f) Any material, compound, mixture, or preparation that contains any quantity of the

8

following substances:

9

     (1) 5-(1,1-Dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (CP-47,497)

10

     (2) 5-(1,1-Dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol

11

(cannabicyclohexanol and CP-47,497 c8 homologue)

12

     (3) 1-Butyl-3-(1 naphthoyl)indole, (JWH-073)

13

     (4) 1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH-200)

14

     (5) 1-Pentyl-3-(1-napthoyl)indole, (JWH-018 and AM678)

15

     (g) Synthetic cannabinoids or piperazines. Unless specifically excepted, any chemical

16

compound which is not approved by the United States Food and Drug Administration or, if

17

approved, which is not dispensed or possessed in accordance with state and federal law, that

18

contains Benzylpiperazine (BZP); Trifluoromethylphenylpiperazine (TFMPP); 1,1-

19

Dimethylheptyl-11-hydroxytetrahydrocannabinol (HU-210); 1-Butyl-3-(1-naphthoyl) indole; 1-

20

Pentyl-3-(1-naphthoyl) indole; dexanabinol (HU-211); or any compound in the following structural

21

classes:

22

     (1) Naphthoylindoles: Any compound containing a 3-(1-naphthoyl)indole structure with

23

substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl,

24

cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl

25

group, whether or not further substituted in the indole ring to any extent and whether or not

26

substituted in the naphthyl ring to any extent. Examples of this structural class include, but are not

27

limited, to JWH-015, JWH-018, JWH-019, JWH-073, JWH-081, JWH-122, JWH-200, and AM-

28

2201;

29

     (2) Phenylacetylindoles: Any compound containing a 3-phenylacetylindole structure with

30

substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl,

31

cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl

32

group whether or not further substituted in the indole ring to any extent and whether or not

33

substituted in the phenyl ring to any extent. Examples of this structural class include, but are not

34

limited to, JWH-167, JWH-250, JWH-251, and RCS-8;

 

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     (3) Benzoylindoles: Any compound containing a 3-(benzoyl) indole structure with

2

substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl,

3

cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl

4

group whether or not further substituted in the indole ring to any extent and whether or not

5

substituted in the phenyl ring to any extent. Examples of this structural class include, but are not

6

limited, to AM-630, AM-2233, AM-694, Pravadoline (WIN 48,098), and RCS-4;

7

     (4) Cyclohexylphenols: Any compound containing a 2-(3-hydroxycyclohexyl)phenol

8

structure with substitution at the 5-position of the phenolic ring by an alkyl, haloalkyl, alkenyl,

9

cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl

10

group whether or not substituted in the cyclohexyl ring to any extent. Examples of this structural

11

class include, but are not limited to, CP 47,497 and its C8 homologue (cannabicyclohexanol);

12

     (5) Naphthylmethylindoles: Any compound containing a 1H-indol-3-yl-(1-naphthyl)

13

methane structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl,

14

alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-

15

morpholinyl)ethyl group whether or not further substituted in the indole ring to any extent and

16

whether or not substituted in the naphthyl ring to any extent. Examples of this structural class

17

include, but are not limited to, JWH-175, JWH-184, and JWH-185;

18

     (6) Naphthoylpyrroles: Any compound containing a 3-(1-naphthoyl)pyrrole structure with

19

substitution at the nitrogen atom of the pyrrole ring by an alkyl, haloalkyl, alkenyl,

20

cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl

21

group whether or not further substituted in the pyrrole ring to any extent and whether or not

22

substituted in the naphthyl ring to any extent. Examples of this structural class include, but are not

23

limited, to JWH-030, JWH-145, JWH-146, JWH-307, and JWH-368;

24

     (7) Naphthylmethylindenes: Any compound containing a 1-(1-naphthylmethyl)indene

25

structure with substitution at the 3-position of the indene ring by an alkyl, haloalkyl, alkenyl,

26

cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl

27

group whether or not further substituted in the indene ring to any extent and whether or not

28

substituted in the naphthyl ring to any extent. Examples of this structural class include, but are not

29

limited to, JWH-176; or

30

     (8) Any other synthetic cannabinoid or piperazine which is not approved by the United

31

States Food and Drug Administration or, if approved, which is not dispensed or possessed in

32

accordance with state and federal law.

33

     (h) Synthetic cathinones. Unless specifically excepted, any chemical compound which is

34

not approved by the United States Food and Drug Administration or, if approved, which is not

 

LC004443 - Page 10 of 20

1

dispensed or possessed in accordance with state and federal law, not including bupropion,

2

structurally derived from 2-aminopropan-1-one by substitution at the 1-position with either phenyl,

3

naphthyl, or thiophene ring systems, whether or not the compound is further modified in one or

4

more of the following ways:

5

     (1) By substitution in the ring system to any extent with alkyl, alkylenedioxy, alkoxy,

6

haloalkyl, hydroxyl, or halide substituents, whether or not further substituted in the ring system by

7

one or more other univalent substituents. Examples of this class include, but are not limited to, 3,4-

8

Methylenedioxycathinone (bk-MDA);

9

     (2) By substitution at the 3-position with an acyclic alkyl substituent. Examples of this

10

class include, but are not limited to, 2-methylamino-1-phenylbutan-1-one (buphedrone);

11

     (3) By substitution at the 2-amino nitrogen atom with alkyl, dialkyl, benzyl, or

12

methoxybenzyl groups, or by inclusion of the 2-amino nitrogen atom in a cyclic structure.

13

Examples of this class include, but are not limited to, Dimethylcathinone, Ethcathinone, and α-

14

Pyrrolidinopropiophenone (α-PPP); or

15

     (4) Any other synthetic cathinone which is not approved by the United States Food and

16

Drug Administration or, if approved, is not dispensed or possessed in accordance with state or

17

federal law. Examples of this class include, but are not limited to, Ephylone and Pentylone.

18

     Schedule II

19

     (a) Substances, vegetable origin, or chemical synthesis. Unless specifically excepted or

20

unless listed in another schedule, any of the following substances whether produced directly or

21

indirectly by extraction from substances of vegetable origin, or independently by means of

22

chemical synthesis, or by a combination of extraction and chemical synthesis:

23

     (1) Opium and opiate, and any salt, compound, derivative, or preparation of opium or

24

opiate excluding naloxone and its salts, and excluding naltrexone and its salts, but including the

25

following:

26

     (i) Raw opium

27

     (ii) Opium extracts

28

     (iii) Opium fluid extracts

29

     (iv) Powdered opium

30

     (v) Granulated opium

31

     (vi) Tincture of opium

32

     (vii) Etorphine hydrochloride

33

     (viii) Codeine

34

     (ix) Ethylmorphine

 

LC004443 - Page 11 of 20

1

     (x) Hydrocodone

2

     (xi) Hydromorphone

3

     (xii) Metopon

4

     (xiii) Morphine

5

     (xiv) Oxycodone

6

     (xv) Oxymorphone

7

     (xvi) Thebaine

8

     (2) Any salt, compound, derivative, or preparation that is chemically equivalent or identical

9

with any of the substances referred to in subdivision (1) of this subsection, except that these

10

substances shall not include the isoquinoline alkaloids of opium.

11

     (3) Opium poppy and poppy straw.

12

     (4) Coca leaves and any salt, compound, derivative, or preparation of coca leaves, and any

13

salt, compound, derivative, or preparation that is chemically equivalent or identical with any of

14

these substances, except that the substances shall not include decocainized coca leaves or extraction

15

of coca leaves, which extractions do not contain cocaine or ecgonine.

16

     (5) Concentrate of poppy straw (the crude extract of poppy straw in liquid, solid, or powder

17

form that contains the phenanthrine alkaloids of the opium poppy).

18

     (b) Opiates. Unless specifically excepted or unless listed in another schedule, any of the

19

following opiates, including its isomers, esters, ethers, salts; and salts of isomers, esters, and ethers

20

whenever the existence of the isomers, esters, ethers, and salts is possible within the specific

21

chemical designation:

22

     (1) Alphaprodine

23

     (2) Anileridine

24

     (3) Bezitramide

25

     (4) Dihydrocodeine

26

     (5) Diphenoxylate

27

     (6) Fentanyl

28

     (7) Isomethadone

29

     (8) Levomethorphan

30

     (9) Levorphanol

31

     (10) Metazocine

32

     (11) Methadone

33

     (12) Methadone-Intermediate, 4-cyano-2-dimethylamino-4, 4-diphenyl butane

34

     (13) Moramide-Intermediate, 2-methyl-3-morpholino-1, 1-diphenylpropane-carboxylic

 

LC004443 - Page 12 of 20

1

acid

2

     (14) Pethidine

3

     (15) Pethidine-Intermediate-A, 4-cyano-1-methyl-4-phenylpiperidine

4

     (16) Pethidine-Intermediate-B, ethyl-4-phenylpiperidine-4-carboxylate

5

     (17) Pethidine-Intermediate-C, 1-methyl-4-phenylpiperidine-4-carboxylic acid

6

     (18) Phenaxocine

7

     (19) Piminodine

8

     (20) Racemethorphan

9

     (21) Racemorphan

10

     (22) Bulk Dextropropoxyphene (non-dosage forms)

11

     (23) Suffentanil

12

     (24) Alfentanil

13

     (25) Levoalphacetylmethadol

14

     (26) Carfentanil

15

     (27) Remifentanil

16

     (c) Stimulants. Unless specifically excepted or unless listed in another schedule, any

17

material, compound, mixture, or preparation that contains any quantity of the following substances

18

having a stimulant effect on the central nervous system:

19

     (1) Amphetamine, its salts, optical isomers, and salts of its optical isomers.

20

     (2) Methamphetamine, its salts, and salts of its isomers.

21

     (3) Phenmetrazine and its salts.

22

     (4) Methylphenidate.

23

     (d) Depressants. Unless specifically excepted or unless listed in another schedule, any

24

material, compound, mixture, or preparation that contains any quantity of the following substances

25

having a depressant effect on the central nervous system, including its salts, isomers, and salts of

26

isomers whenever the existence of the salts, isomers, and salts of isomers is possible within the

27

specific chemical designation:

28

     (1) Amobarbital

29

     (2) Glutethimide

30

     (3) Methyprylon

31

     (4) Pentobarbital

32

     (5) Phencyclidine

33

     (6) Secobarbital

34

     (7) Phencyclidine immediate precursors:

 

LC004443 - Page 13 of 20

1

     (i) 1-phencyclohexylamine

2

     (ii) 1-piperidinocyclohexane-carbonitrile (PCC)

3

     (8) Immediate precursor to amphetamine and methamphetamine: Phenylacetone. Some

4

other names: phenyl-2-propanone; P2P; benzyl methyl ketone; methyl benzone ketone.

5

     Schedule III

6

     (a) Unless specifically excepted or unless listed in another schedule, any material,

7

compound, mixture, or preparation that contains any quantity of the following substances having a

8

depressant effect on the central nervous system:

9

     (1) Any substance that contains any quantity of a derivative of barbituric acid or any salt

10

of a derivative of barbituric acid.

11

     (2) Chlorhexadol

12

     (3) Lysergic acid

13

     (4) Lysergic acid amide

14

     (5) Sulfondiethylmethane

15

     (6) Sulfonethylmethane

16

     (7) Sylfonmethane

17

     (8) Any compound, mixture, or preparation containing amobarbital, secobarbital,

18

pentobarbital, or any salt of them and one or more other active medicinal ingredients that are not

19

listed in any schedule.

20

     (9) Any suppository dosage form containing amobarbital, secobarbital, pentobarbital, or

21

any salt of any of these drugs and approved by the Food and Drug Administration for marketing

22

only as a suppository.

23

     (10) Ketamine, its salts, isomers, and salts of isomers. (Some other names for ketamine:

24

(+)-2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone).

25

     (b) Unless specifically excepted or unless listed in another schedule, any material,

26

compound, mixture, or preparation containing limited quantities of any of the following narcotic

27

drugs, or any salts of them:

28

     (1) Not more than one and eight tenths grams (1.8 gms.) of codeine per one hundred

29

milliliters (100 mls.) or not more than ninety milligrams (90 mgs.) per dosage unit, with an equal

30

or greater quantity of an isoquinoline alkaloid of opium.

31

     (2) Not more than one and eight tenths grams (1.8 gms.) of codeine per one hundred

32

milliliters (100 mls.) or not more than ninety milligrams (90 mgs.) per dosage unit, with one or

33

more active, nonnarcotic ingredients in recognized therapeutic amounts.

34

     (3) Not more than three hundred milligrams (300 mgs.) of dihydrocodeinone per one

 

LC004443 - Page 14 of 20

1

hundred milliliters (100 mls.) or not more than fifteen milligrams (15 mgs.) per dosage unit, with

2

a fourfold or greater quantity of an isoquinoline alkaloid of opium.

3

     (4) Not more than three hundred milligrams (300 mgs.) of dihydrocodeinone per one

4

hundred milliliters (100 mls.) or not more than fifteen milligrams (15 mgs.) per dosage unit, with

5

one or more active nonnarcotic ingredients in recognized therapeutic amounts.

6

     (5) Not more than one and eight tenths grams (1.8 gms.) of dihydrocodeine per one hundred

7

milliliters (100 mls.) or not more than ninety milligrams (90 mgs.) per dosage unit, with one or

8

more active nonnarcotic ingredients in recognized therapeutic amounts.

9

     (6) Not more than three hundred milligrams (300 mgs.) of ethylmorphine per one hundred

10

milliliters (100 mls.) or not more than fifteen milligrams (15 mgs.) per dosage unit, with one or

11

more active nonnarcotic ingredients in recognized therapeutic amounts.

12

     (7) Not more than five hundred milligrams (500 mgs.) of opium per one hundred milliliters

13

(100 mls.) or per one hundred grams (100 gms.) or not more than twenty-five milligrams (25 mgs.)

14

per dosage unit, with one or more active nonnarcotic ingredients in recognized therapeutic amounts.

15

     (8) Not more than fifty milligrams (50 mgs.) of morphine per one hundred milliliters (100

16

mls.) per one hundred grams (100 gms.) with one or more active, nonnarcotic ingredients in

17

recognized therapeutic amounts.

18

     (c) Stimulants. Unless specifically excepted or listed in another schedule, any material,

19

compound, mixture, or preparation that contains any quantity of the following substances having a

20

stimulant effect on the central nervous system, including its salts, isomers, and salts of the isomers

21

whenever the existence of the salts of isomers is possible within the specific chemical designation:

22

     (1) Benzphetamine

23

     (2) Chlorphentermine

24

     (3) Clortermine

25

     (4) Mazindol

26

     (5) Phendimetrazine

27

     (d) Steroids and hormones. Anabolic steroids (AS) or human growth hormone (HGH),

28

excluding those compounds, mixtures, or preparations containing an anabolic steroid that because

29

of its concentration, preparation, mixture, or delivery system, has no significant potential for abuse,

30

as published in 21 C.F.R. § 1308.34, including, but not limited to, the following:

31

     (1) Chorionic gonadotropin, except for veterinary use and when that use is approved by the

32

Food and Drug Administration.

33

     (2) Clostebol

34

     (3) Dehydrochlormethyltestosterone

 

LC004443 - Page 15 of 20

1

     (4) Ethylestrenol

2

     (5) Fluoxymesterone

3

     (6) Mesterolone

4

     (7) Metenolone

5

     (8) Methandienone

6

     (9) Methandrostenolone

7

     (10) Methyltestosterone

8

     (11) Nandrolone decanoate

9

     (12) Nandrolone phenpropionate

10

     (13) Norethandrolone

11

     (14) Oxandrolone

12

     (15) Oxymesterone

13

     (16) Oxymetholone

14

     (17) Stanozolol

15

     (18) Testosterone propionate

16

     (19) Testosterone-like related compounds

17

     (20) Human Growth Hormone (HGH)

18

     (e) Hallucinogenic substances.

19

     (1) Dronabinol (synthetic) in sesame oil and encapsulated in a soft gelatin capsule in U.S.

20

Food and Drug Administration-approved drug product. (Some other names for dronabinol: (6aR-

21

trans)-6a, 7, 8, 10a-tetrahydro-6, 6, 9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol, or (-)-delta-

22

9(trans)-tetrahydrocannabinol.)

23

     Schedule IV

24

     (1) Barbital.

25

     (2) Chloral betaine

26

     (3) Chloral hydrate

27

     (4) Ethchrovynol

28

     (5) Ethinamate

29

     (6) Methohexital

30

     (7) Meprobamate

31

     (8) Methylphenobarbital

32

     (9) Paraldehyde

33

     (10) Petrichloral

34

     (11) Phenobarbital

 

LC004443 - Page 16 of 20

1

     (12) Fenfluramine

2

     (13) Diethylpropion

3

     (14) Phentermine

4

     (15) Pemoline (including organometallic complexes and chelates thereof).

5

     (16) Chlordiazepoxide

6

     (17) Clonazepam

7

     (18) Clorazepate

8

     (19) Diazepam

9

     (20) Flurazepam

10

     (21) Mebutamate

11

     (22) Oxazepam

12

     (23) Unless specifically excepted or unless listed in another schedule, any material,

13

compound, mixture, or preparation that contains any quantity of the following substances, including

14

its salts:

15

     Dextropropoxyphene(alpha-(+)-4-dimethylamino-1,2-diphenyl-3-methyl-2-

16

propronoxybutane).

17

     (24) Prazepam

18

     (25) Lorazepam

19

     (26) Not more than one milligram (1 mg.) of difenoxin and not less than twenty-five (25)

20

micrograms of atropine sulfate per dosage unit.

21

     (27) Pentazocine

22

     (28) Pipradrol

23

     (29) SPA (-)-1-dimethylamino-1, 2-diphenylethane

24

     (30) Temazepam

25

     (31) Halazepam

26

     (32) Alprazolam

27

     (33) Bromazepam

28

     (34) Camazepam

29

     (35) Clobazam

30

     (36) Clotiazepam

31

     (37) Cloxazolam

32

     (38) Delorazepam

33

     (39) Estazolam

34

     (40) Ethyl Ioflazepate

 

LC004443 - Page 17 of 20

1

     (41) Fludizaepam

2

     (42) Flunitrazepam

3

     (43) Haloxazolam

4

     (44) Ketazolam

5

     (45) Loprazolam

6

     (46) Lormetazepam

7

     (47) Medazepam

8

     (48) Nimetazepam

9

     (49) Nitrazepam

10

     (50) Nordiazepam

11

     (51) Oxazolam

12

     (52) Pinazepam

13

     (53) Tetrazepam

14

     (54) Mazindol

15

     (55) Triazolam

16

     (56) Midazolam

17

     (57) Quazepam

18

     (58) Butorphanol

19

     (59) Sibutramine

20

     (60) Tramadol

21

     (61) Zolpidem

22

     Schedule V

23

     (a) Any compound, mixture, or preparation containing any of the following limited

24

quantities of narcotic drugs, which shall include one or more non-narcotic active medicinal

25

ingredients in sufficient proportion to confer upon the compound, mixture, or preparation valuable

26

medicinal qualities other than those possessed by the narcotic drug alone:

27

     (1) Not more than two hundred milligrams (200 mgs.) of codeine per 100 milliliters (100

28

mls.) or per one hundred grams (100 gms.).

29

     (2) Not more than one hundred milligrams (100 mgs.) of dihydrocodeine per 100 milliliters

30

(100 mls.) or per one hundred grams (100 gms.).

31

     (3) Not more than one hundred milligrams (100 mgs.) of ethylmorphine per 100 milliliters

32

(100 mls.) or per one hundred grams (100 gms.).

33

     (4) Not more than two and five tenths milligrams (2.5 mgs.) of diphenixylate and not less

34

than twenty-five (25) micrograms of atropine sulfate per dosage unit.

 

LC004443 - Page 18 of 20

1

     (5) Not more than one hundred milligrams (100 mgs.) of opium per one hundred milliliters

2

(100 mls.) or per one hundred grams (100 gms.).

3

     (b) Not more than five tenths milligrams (0.5 mgs.) of difenoxin and not less than twenty-

4

five (25) micrograms of atropine sulfate per dosage unit.

5

     (c) Buprenorphine

6

     (d) Unless specifically exempted or excluded or unless listed in another schedule, any

7

material, compound, mixture, or preparation that contains any quantity of the following substances

8

having a stimulant effect on the central nervous system, including its salts, isomers, and salts of

9

isomers:

10

     (1) Propylhexedrine (except as benzedrex inhaler)

11

     (2) Pyrovalerone.

12

     (e) Xylazine HCL

13

     21-28-2.09. Exemption of compounds containing counteragents.

14

     Nothing in this chapter shall apply to any compound, mixture, or preparation containing

15

any depressant or stimulant drug in schedule II or in subsection (a) of schedule III or in schedule

16

IV or V if: (1) the compound, mixture, or preparation contains one or more active medicinal

17

ingredients not having a depressant or stimulant effect on the central nervous system, and (2) these

18

ingredients are included in the compound, mixture or preparation in such combinations, quantity,

19

proportion, or concentration as to vitiate the potential for abuse of the drugs which do have a

20

depressant or stimulant effect on the central nervous system.

21

     21-28-2.10. Exemption of dextromethorphan.

22

     Dextromethorphan shall not be deemed to be included in any schedule unless controlled

23

pursuant to the provisions of this article.

24

     SECTION 3. This act shall take effect upon passage.

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LC004443

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LC004443 - Page 19 of 20

EXPLANATION

BY THE LEGISLATIVE COUNCIL

OF

A N   A C T

RELATING TO FOOD AND DRUGS -- UNIFORM CONTROLLED SUBSTANCES ACT

***

1

     This act would substitute the current lists of controlled substances in the general laws with

2

the current version of Title 21 of the code of federal regulations.

3

     This act would take effect upon passage.

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LC004443

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LC004443 - Page 20 of 20